Cannabis May Be Replaced by Beer’s Best Ingredient for Pain Therapy

Cannabidiol, one of the active chemicals in marijuana, is having a moment. While the science remains inconclusive, there’s growing traction for its use as a therapeutic agent for cancer and schizophrenia, and for its inclusion within more cosmetic items, like CBD-infused bath bombs and acne creams. What makes CBD novel is that it, unlike THC, is a cannabinoid chemical that comes without the high — although as a fixture of a Schedule I drug, in some places, it still comes with the stigma.

In October, Isodiol International Inc.)), a company that claims it is “the largest global industrial source of CBD hemp oil worldwide,” announced its plan to release the market’s first CBD products derived from hops — the cone-shaped flowers responsible for flavoring and stabilizing beer.

While 29 states and the District of Columbia have legalized marijuana in some form, all cannabis extracts, including CBD, are still ruled federally as Schedule I substances. With the attorney general post belonging to Jeff Sessions, that ruling won’t likely change anytime soon. Hops, meanwhile, are legal everywhere.

As cannabidiol continues to be explored for its therapeutic potential as a treatment for disorders that include, but aren’t limited to, anxiety, schizophrenia, and cancer, it will be interesting to see whether other companies and universities follow Ursodiol in the study of CBD derived from hops. The illegality of cannabis has made it difficult for scientists to research its benefits, but hops could be a promising route when it comes to exploring how CBD can help people heal.

Read the full article at Inverse

Is Marijuana In Candy A Real Concern This Halloween?

Before you send your kids out for Halloween, warn them about the dangers they could encounter. Wear reflective clothing, carry a flashlight, look both ways before crossing the street and it is never a good idea to go into someone’s house.

The other concern this year is to be on the lookout for people slipping kids marijuana-laced candy. It is always a good idea to remind your kids to have an adult inspect all candy before eating it.

“You probably can’t tell the difference between medicated gummy bears and the regular ones if you put them side by side,” said Encanto Greens owner Bill Brothers.

All the edibles sold at his store are manufactured someone else and sold locally. The packaging does list marijuana on it but it is often small and the box or wrapping looks like a candy wrapper.

“I think there is an opportunity to improve the labeling of medical marijuana, especially in edibles,” said Brothers.

But is there a significant physical danger if your child were to ingest marijuana found in cookies or gummy bears?

Experts warn parents and kids to never accept treats that don’t come in the original wrapping and always wait to get home and inspect the candy or sweets before eating it.

Full article at 10 News

How Coca Leaf Became Colombia’s New Superfood

No other plant in human history has been as demonized as coca.

In 1961, it was placed on the Schedule I list at the United Nations Single Convention on Narcotic Drugs, which stated that “The Parties shall so far as possible enforce the uprooting of all coca bushes which grow wild. They shall destroy the coca bushes if illegally cultivated.” The plant has been public enemy number one in the worldwide War on Drugs for decades.

But when the World Health Organization announced last year that the Monsanto-made pesticide, glyphosate, was actually highly carcinogenic, Colombia’s days of kissing America’s ass came to a screeching halt. In an abrupt turnaround, Colombia’s president Juan Manuel Santos is now challenging the War on Drugs in its entirety; this a reflection of the national psyche of a country that has borne the brunt of failed policies for far too long and is ready for real change.

“We are trying to promote the proper use of this plant, as it has been perverted for centuries, and show how it is actually used as indigenous tradition,” says Ximena Robayo, who runs the restaurant/café/health food store in the heart of the city’s bohemian La Candelaria district.

Besides chewing the leaves of coca, or brewing them into a tea, a wide variety of cooked and baked goods and dishes can be made with coca by grinding the leaves into a flour, called harina. This harina can also be stirred into juices, blended in smoothies, and used to make green drinks of all types.

Read the full article at Q Costa Rica

Maine Lawmakers To Debate Sale Of Marijuana

AUGUSTA (WGME) – Maine voters approved recreational marijuana nearly a year ago, but there is still no market set up in the state.

The marijuana debate has yet to happen in the house or senate, but what we do know is Governor LePage and House Republicans seem to be ready to delay the sale of recreational marijuana in Maine.

Portland Senator Mark Dion says the marijuana legalization implementation committee he serves on worked for eight months on a bill that allows for the safe, regulated, taxed and legal sale of marijuana in Maine, which Maine voters approved.

But House Republican Leader Ken Fredette says the bill passed out of committee is far from ready. That’s why he is presenting a governor’s bill to delay the regulated sale of marijuana in Maine.

“There needs to be rulemaking done as part of passing this bill,” Fredette said. “And that rulemaking, in my opinion, is not going to be done anywhere near Feb. 1, 2018.”

The Republican chair of the Marijuana Legalization Committee says there is no need for a delay.

Read more at WGME

Can Cannabis Oil Boost Tilapia Development?

A team of scientists from the American University of Beirut fed Nile tilapia fish pellets laced with cannabis oil to test whether the drug could make the fish reduce stress and grow faster.

These researchers noted that tilapia is farmed intensively, and in a bid to maximize the amount of product fish farmers can bring to market, some fish pens have become incredibly congested. Living in such close quarters can lead to all kinds of challenges for the fish, including reduced water quality, more incidences of disease, and increasing intraspecific interactions, which leads to stress.

As part of the trial, three diets were made to contain either soy oil, industrial hemp oil or cannabis oil and offered to tilapia for 8 weeks. At termination, survival, growth, feed conversion and blood parameters were assessed.

On the other hand, cannabis had no effect on blood cell counts, total plasma protein, hematocrit or lysozyme activity.

The results thus obtained suggest that cannabis does not improve the immune response of tilapia or body composition but does reduce growth rate by increasing metabolic rate.

Therefore, the Lebanese scientists found that the pot pellets did not quite have the mood-altering effect they had hoped for.

Continue Reading at Fish Info & Services Co.Ltd

Greek Official Calls For Marijuana Legalization

On Greek TV, a Greek official calls for marijuana legalization for recreational purposes. The official in question is Yiannis Tsironis. He’s the Deputy Minister for Agriculture, originating from Greece’s Green Party. Yeah, we figured as much.

The Green in Green

Like many other countries, our own included, Greek federal policy outlaws cannabis.

Despite the country’s history of producing hashish, authorities officially criminalized the plant in 1890. Although the cultivation and possession of hashish were illegal, Greek citizens continued to use it. Particularly after the first World War.

This year, the Greek Prime Minister, Alexis Tsipras, legalized marijuana for medicinal purposes, thus becoming the latest European country to implement a nation-wide medical marijuana program. At the moment, weed is still illegal for recreational purposes.

But will it always be?

Continue Reading at High Times

Magic Mushrooms’ Might Ease Depression Symptoms

Psilocybin, the main ingredient in “magic mushrooms,” may soothe symptoms of depression, according to a very preliminary study.

The research had a small sample size — only 20 patients — and no control group who got a placebo for comparison’s sake. That makes it hard to draw firm conclusions about if or how well the hallucinogenic compound really works at fighting depression. But brain-scan data from the new research suggests that psilocybin does impact brain networks that are associated with depression.

Stubborn Depression

The researchers focused on 20 people who had tried standard depression treatments and found them lacking. Each participant, classified as having treatment-resistant depression, took a 10-milligram dose of psilocybin, followed by another 25 milligrams one week later, enough to cause hallucinogenic effects.

The immediately striking finding was that taking psilocybin, which occurs naturally in hundreds of mushroom species, decreased depression symptoms significantly.

A new form of treatment?

“Based on what we know from various brain-imaging studies with psychedelics, as well as taking heed of what people say about their experiences, it may be that psychedelics do indeed ‘reset’ the brain networks associated with depression, effectively enabling them to be lifted from the depressed state,” study leader Robin Carhart-Harris, the head of psychedelic research at Imperial College, said in a statement.

Read the full article at Live Science

Warn Experts: E-Cigarettes Being Adapted To Smoke Illegal Drugs!

Electronic cigarettes are being used to vape illegal substances like cannabis, crack cocaine, ecstasy, and heroin as part of a disturbing new drugs culture.

A study by public health experts has revealed alarming numbers of e-cigarette users are modifying their vaping devices so they can inhale vapor from banned drugs.

The research found 39 percent of people with electronic vaping devices admit to using them to take illegal drugs or former ‘legal highs’ such as mephedrone.

The researchers who led the study warned too little is known about the risks of taking drugs in this way and that it could easily lead to overdoses among other problems.

Read the full article in Daily Mail UK

Magic Mushroom Chemical Appears to Physically Change Depressed Brains

Magic mushrooms are a strange drug. They’re one part illegal music festival enhancer, one part promising treatment that could have important medical applications. That second use continues to look more and more promising.

A new study from researchers in the United Kingdom and South Africa monitored the brains of folks trying psilocybin, the magic mushroom chemical, for depression that wasn’t kicked by the usual treatments. The psychedelic not only reduced the symptoms of depression but seemed to have a noticeable physical effect.

The study followed 15 male and four female depressed patients (which ultimately became 12 and then 11 male patients) receiving two doses of the drug over two weeks, who were then monitored for five weeks after. All of the patients had fewer symptoms of depression in the first week, and around half showed improvement at five weeks.

The paper points out that this is a tiny study with no control, and the researchers reminded New Scientist that you shouldn’t try to self-medicate with psychedelics. But it’s also promising. “This is further evidence that psilocybin may turn out to be effective for the most stubborn depression,” Paul Morrison from King’s College London told them.

Read the full article at Gizmodo

Study: Magic Mushrooms ‘Reboot’ Brain In Depressed People

Magic mushrooms may effectively “reset” the activity of key brain circuits known to play a role in depression, the latest study to highlight the therapeutic benefits of psychedelics suggests.

A neuroscientist explains: the need for ‘empathetic citizens’ – podcast
Psychedelics have shown promising results in the treatment of depression and addictions in a number of clinical trials over the last decade. Imperial College London researchers used psilocybin – the psychoactive compound that occurs naturally in magic mushrooms – to treat a small number of patients with depression, monitoring their brain function, before and after.

“Psilocybin may be giving these individuals the temporary ‘kick start’ they need to break out of their depressive states and these imaging results do tentatively support a ‘reset’ analogy. Similar brain effects to these have been seen with electroconvulsive therapy.”

For the study, published in Scientific Reports on Friday, 20 patients with treatment-resistant depression were given two doses of psilocybin (10 mg and 25 mg), with the second dose a week after the first. Of these, 19 underwent initial brain imaging and then the second scan one day after the high dose treatment. The team used two main brain imaging methods to measure changes in blood flow and the crosstalk between brain regions, with patients reporting their depressive symptoms through completing clinical questionnaires.

The authors believe the findings provide a new window into what happens in the brains of people after they have ‘come down’ from a psychedelic, with an initial disintegration of brain networks during the drug ‘trip’ followed by a re-integration afterward.

Full article at The Guardian

Los Angeles County Issues Its First Cannabis License

Yvonne Delarosa Green was awarded the first cannabis business license for Los Angeles County for her dispensary 99 High Tide Collective in Malibu. The city and county of Los Angeles are expected to become the capital of cannabis once the state of California’s regulated adult-use market is up and running.

There is a great deal of confusion over the cannabis licenses in the city versus the county. Los Angeles, the city, hasn’t issued any licenses, and it is rumored that existing dispensaries will have to close until they receive the new 2018 license under the new regulations.

Keith Knox, chief deputy treasurer and tax collector for the county, confirmed that Los Angeles County administers some functions like business permits for three cities and Malibu is one of those three. However, Los Angeles County is banning marijuana for now, which makes the licensing in Malibu even more unique.

The mayor’s office in Malibu said in a statement:

“The City of Malibu’s Municipal Code allows for two medical marijuana dispensaries to operate within City limits. Two medical marijuana dispensaries have been in operation in the City for several years. Los Angeles County issues business licenses on behalf of the City of Malibu, and approved a business license for one of the two existing medical marijuana dispensaries today.”

Read the full article at Forbes

Home Brewed Death Tea

Poppy seed tea has potentially lethal consequences according to a new paper published in the Journal of Forensic Sciences. Researchers at Sam Houston State University decided to look into home-brewed poppy seed tea and its lethality.

Deaths attributable to opioids have quadrupled since 1999 and account for the six out of every ten overdose deaths. Whereas heroin and opiate-containing medications have been the primary source of addictions and deaths, it seems that brewing tea from unwashed poppy seeds can also kill.

The opium poppy plant (Papaver somniferum) has been cultivated for centuries as a source of opium. Poppy seeds produced from the poppy plant produce a milky sap containing opiates. Poppy seed tea is made by washing or soaking the seeds in water. Opium is contained within the seed capsule and also contains a variable mixture of alkaloids, including roughly ten percent morphine, 6 percent noscapine, one percent papaverine, 0.5 percent codeine and 0.2 percent thebaine.

How lethal ingestion of opiates can depend on individual tolerance which develops rapidly with long-term use. As the authors of the study point out, “The level of information that is shared online contributes to the facilitation of drug abuse practices such as extracting opium alkaloids by brewing poppy seed tea,” and they add, “However, this practice can have fatal consequences.”

Professor Madeleine Swortwood, an Assistant Professor in the Department of Forensic Science at Sam Houston State University, was contacted by the parent of a young man who died after drinking home-brewed PST.

Read more at American Council on Science and Health

Opium Tincture Market Plan, Supply and Revenue to 2020

A tincture is an alcoholic extract of plant or animal material or solution of such low volatility substance. Tincture of opium which is also known as laudanum is an alcoholic herbal preparation containing approximately 10% powdered opium by weight.

Opium is a highly narcotic drug acquired as dried latex that contains approximately 12% of the analgesic alkaloid morphine. Opium is processed chemically to produce heroin and other synthetic opioids for medicinal use and other uses. Opium tincture is reddish brown in color and bitter in taste.

Opium tincture contains morphine and codeine and it is primarily used as an analgesic and cough suppressant. Opium tincture enhances the tone in the long segments of the longitudinal muscle and inhibits propulsive contraction of circular and longitudinal muscles.

Opium tincture remains in the British Pharmacoepia, where it is referred to as Tincture of Opium, B.P., Laudanum, Thebaic Tincture, or Tinctura Thebaica.
Major methods of preparation of opium include processing it into regular opium tincture (tinctura opii).

Read the full article at Miltech

State To Miss Deadline For Marijuana Licenses

TALLAHASSEE — Health officials won’t be able to meet a legislatively mandated Tuesday deadline to hand out five new medical-marijuana licenses, the head of the state’s Office of Medical Marijuana Use said Friday.

The law called for an overall increase of 10 licenses, some of which have already been awarded, by Oct. 3. It also specified that one license goes to a black farmer who had been part of settled lawsuits about discrimination by the federal government against black farmers.

In a letter to legislative leaders signed Friday, Bax wrote that his office has “worked diligently to implement” the new law, but that the issuance of five new medical marijuana licenses by Tuesday posed an “extraordinarily challenging deadline.”

Bax pointed out that 13 administrative challenges were filed after the agency issued the first medical-marijuana licenses in 2015. The agency is still in litigation over two of the challenges, he said.

The upcoming licenses will be the first time the state has opened the application process to businesses that did not participate in the first selection process in 2015, creating intense interest in what could be one of the biggest medical-marijuana markets in the nation.

Read more at Newsherald

Cannabis Oil Dabbing Might Expose You To Malign Toxins

American Chemical Society’s ACS Omega has published a study which claims to be groundbreaking in terms of how we view a very specific type of cannabis consumption, the so-called cannabis oil dabbing.

The study which was published this month finds that dabbing cannabis oil through glass rigs may expose users to elevated toxin levels as compared to other methods, such as smoking dried cannabis or even vaping it for that matter.

In an effort to explain how the chemicals in concentrated cannabis break down under heat, a team of scientists from Portland State University has discovered that concentrates exposed to the high heat common to dab setups produced elevated levels of carcinogenic and toxic compounds.

Dabbing at low temperatures might be the way out

Researchers from PSU said that the key factor in which chemicals get released is the degree of heat used to activate cannabinoids in the oil.

Researchers also found that the higher the temperature that a substance’s flavoring terpenes are subjected to, the more carcinogens, toxins, and potential irritants are produced — meaning that you should dab on as low as possible temperatures.

Read the full article at Greencamp

Why Is Weed Getting More Potent?

The feds began monitoring the potency of the nation’s pot supply in the ‘70s by drawing samples from stashes seized by law enforcement, and boy was it schwag. The percentage of THC—the main psychoactive component in cannabis—averaged from less than 1% in 1975 to just under 3% a decade later, according to the data.

These notoriously low levels reflected the times, as the weed subculture in America was just starting to take root and could help explain why some of the most memorable old school brands have names like Acapulco Gold, Panama Red, Afghani, Thai stick, and Jamaican sensi; they were all originally cultivated outside of the country.

Now, as some critics have pointed out, it’s impossible to empirically confirm how strong domestically grown pot was back in the day due to inferior testing and sampling methods, however, there does seem to be enough prevailing research, firsthand testimony, and common sense to show that the illicit reefer from decades ago wasn’t nearly as powerful as today’s.

A recent federal study found that “the potency of illicit cannabis plant material has consistently risen over time since 1995 from approximately 4% in 1995 to approximately 12% in 2014.” This marked increase represents a shift when smokers began to pivot from dirt to mid-grade and hydro. In one standout bust from 2009, the DEA nabbed some sticky-icky that scored an impressive 33.12%, the highest concentration of THC the agency has ever seen in a domestic sample of weed.

Continue Reading at Gizmodo

CDC Launches Campaign To Fight Opioid Crisis In US

The Centers for Disease Control and Prevention has launched a national campaign to help fight the prescription opioid crisis in this country.

The campaign will use online advertising, billboards, newspapers and radio/TV ads to increase awareness about the risks of opioids.

“The U.S. Department of Health and Human Services is committed to using evidence-based methods to communicate targeted messages about the opioid crisis and prevent addiction and misuse in every way we can,” said HHS Secretary Tom Price, M.D.

He added, “Prevention is a key piece of the five-point strategy HHS unveiled under the Trump Administration for combating this crisis, which has left no corner of America untouched.”

WSB Radio

Surprising Medical Marijuana Side Effect: More People Claiming Disability

Medical marijuana laws are becoming more popular across the country, but legalizing the drug for medicinal purposes can have a major unintended consequence.

State medical marijuana laws lead to an increase in the probability that people will make Social Security Disability Insurance (SSDI) claims, according to a new working paper from researchers at Temple University, Johns Hopkins University and the University of Cincinnati. The tendency to make a SSDI claim rose 9.9% following the passage of a medical marijuana law, while actual SSDI benefits rose by 2.6%. The report, which was distributed by the National Bureau of Economic Research, used data from the Current Population Survey by the Bureau of Labor Statistics to produce its findings.

The researchers also studied the effect state laws on medical marijuana had on workers’ compensation (WC) claims. While their analysis did not produce any statistically significant evidence for these claims, the researchers said the data suggested generally that the laws do cause an increase. “Expanding marijuana access has negative spillover effects to costly social programs that disincentive work,” the researchers wrote.

More of this news at Marketwatch

WING Officials Report Increase In Heroin Usage

GERING — Scotts Bluff County Sheriff Mark Overman refers to Colorado as the area’s “canary in the coal mine” because law enforcement and drug problems experienced in northern Colorado soon spread to the Nebraska Panhandle.

Use of the powerful painkillers, both prescription and non-prescription, has been rapidly increasing in both the U.S. and Canada since about 2010. By 2015, overdose deaths from opioids surpassed deaths from both car accidents and guns.

According to the Drug Enforcement Administration, overdose deaths, especially from prescription opioids and heroin, have reached epidemic levels.

Nebraska State Patrol Sgt. Brian Eads serves as the WING Drug Task Force commander. He said the area has been dealing with opioids, particularly prescription drugs, for some time. But now heroin is starting to make more of an appearance in even smaller towns in the Panhandle.

Much of the heroin they’re seeing is cut with fentanyl, a synthetic opioid painkiller that has a rapid onset and short duration of action. It’s 50 to 100 times more potent than morphine.

Eads said DEA statistics show a large majority of seized heroin has been cut with fentanyl, which is considerably stronger than the heroin itself.

Read more at Starherald

High Number of Applicants for Arkansas Medical Marijuana

LITTLE ROCK, Ark. (AP) — Would-be growers and distributors of Arkansas’ initial medical marijuana crop flooded a state office building Monday, turning in thousands of pages of paperwork and handing over thousands of dollars in application fees.

Arkansas voters last year approved marijuana use by people with certain medical conditions. The new state Medical Marijuana Commission will review applications after the names of companies and individuals have been redacted and then select up to five growers and 32 distributors. The Arkansas Health Department has approved 1,200 people for a medical marijuana registry, making them eligible to obtain the drug.

Continue Reading at US News